Name: GNF362
Rating: 4 (6 reviews)

In Stock

SDF File

Edit Structure

Find Similar

HIT ID:HIT218659277
Cas No:1003019-41-7
Common Name:GNF362
alias:GNF-362, GNF 362
IUPAC:4-(4-{[(3R)-3-methyl-4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methyl}-1H-pyrazol-3-yl)benzonitrile
IUPAC:4-(4-{[(3R)-3-methyl-4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methyl}-1H-pyrazol-3-yl)benzonitrile
InChIKey:VNTCGXMLDSKOKN-OAHLLOKOSA-N

Molecular Formula:C22H21F3N6
Molecular Weight:426.447
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:C[C@@H]1CN(Cc2c[nH]nc2-c2ccc(cc2)C#N)CCN1c1ccc(cn1)C(F)(F)F
SMILES:C[C@@H]1CN(Cc2c[nH]nc2-c2ccc(cc2)C#N)CCN1c1ccc(cn1)C(F)(F)F

GNF362 is an orally available, selective and potent inhibitor of inositol trisphosphate 3'kinase B (ITPKB), inhibits Itpka and Itpkc, overcomes TMZ chemoresistance, and selectively deletes donor allogeneic reactive T-cells.GNF362 reverses the migratory stimulatory effects of ITPKA overexpression.

Marketplace OffersShowing from 1 suppliers

You cannot determine which compound library is the best fit for your project? Do you need a custom solution? AnyMol is always ready to help you.

：400-820-0310

Loading ~