Name: MU1210
Rating: 4 (6 reviews)

In Stock

SDF File

Edit Structure

Find Similar

HIT ID:HIT218667083
Cas No:2275601-87-9
Common Name:MU1210
IUPAC:4-{3-[5-(1-methyl-1H-pyrazol-4-yl)furo[3,2-b]pyridin-3-yl]phenyl}pyridine
IUPAC:4-{3-[5-(1-methyl-1H-pyrazol-4-yl)furo[3,2-b]pyridin-3-yl]phenyl}pyridine
InChI key:HEAGNKNMQVIVMM-UHFFFAOYSA-N

Molecular Formula:C22H16N4O
Molecular Weight:352.397
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:Cn1cc(cn1)-c1ccc2occ(-c3cccc(c3)-c3ccncc3)c2n1
SMILES:Cn1cc(cn1)-c1ccc2occ(-c3cccc(c3)-c3ccncc3)c2n1

MU1210 (compound 12f) acts as an inhibitor of CDC-like kinases Clk1, Clk2, and Clk4 with IC50 values of 8, 20, and 12 nM, respectively, and exhibits IC50 values of 187 and 1309 nM for HIPK1 and DYRK2. Additionally, MU1210 demonstrates favorable pharmacokinetic properties in mice (10 mg/kg, intraperitoneal injection: Cmax=1.24 μM, T1/2=58 minutes; no acute toxicity observed).

Marketplace OffersShowing from 1 suppliers

You cannot determine which compound library is the best fit for your project? Do you need a custom solution? AnyMol is always ready to help you.

：400-820-0310

Loading ~