Name: Pomalidomide-5-C8-NH2 hydrochloride
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HIT ID:HIT218667160
Cas No:
Common Name:Pomalidomide-5-C8-NH2 hydrochloride
Common Name:Pomalidomide-5-C8-NH2 hydrochloride
IUPAC:5-[(8-aminooctyl)amino]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride
IUPAC:5-[(8-aminooctyl)amino]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride
InChIKey:FMSPEHPBLAHHCK-UHFFFAOYSA-N

Molecular Formula:C21H29ClN4O4
Molecular Weight:436.94
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:Cl.NCCCCCCCCNc1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1
SMILES:Cl.NCCCCCCCCNc1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1

Pomalidomide-5-C8-NH2 hydrochloride, a Pomalidomide-based cereblon (CRBN) ligand, is instrumental in the recruitment of CRBN protein. This compound can be linked to the protein ligand via a linker to form PROTAC ^[1].

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