Name: DC271
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HIT ID:HIT218671916
Cas No:
Common Name:DC271
alias:DC-271, DC271, DC 271
IUPAC:4-{2-[4,4-dimethyl-1-(propan-2-yl)-1,2,3,4-tetrahydroquinolin-6-yl]ethynyl}benzoic acid
IUPAC:4-{2-[4,4-dimethyl-1-(propan-2-yl)-1,2,3,4-tetrahydroquinolin-6-yl]ethynyl}benzoic acid
InChI key:OCMSZODRCJAGHL-UHFFFAOYSA-N

Molecular Formula:C23H25NO2
Molecular Weight:347.458
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:CC(C)N1CCC(C)(C)c2cc(ccc12)C#Cc1ccc(cc1)C(O)=O
SMILES:CC(C)N1CCC(C)(C)c2cc(ccc12)C#Cc1ccc(cc1)C(O)=O

DC271, a retinoid and RAR agonist, mimics the cellular effects of the endogenous ATRA and the synthetic EC23, by binding to retinoid protein machinery such as CRABPII to facilitate the translocation of ATRA into the nucleus [1].

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