Name: (Rac)-AMXT-1501 4HCl
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HIT ID:HIT218674550
Cas No:2771343-93-0
Common Name:(Rac)-AMXT-1501 4HCl
IUPAC:N-(5-amino-5-{[3-({4-[(3-aminopropyl)amino]butyl}amino)propyl]carbamoyl}pentyl)hexadecanamide tetrahydrochloride
IUPAC:N-(5-amino-5-{[3-({4-[(3-aminopropyl)amino]butyl}amino)propyl]carbamoyl}pentyl)hexadecanamide tetrahydrochloride
InChIKey:HUWZIAHAQAFYJQ-UHFFFAOYSA-N

Molecular Formula:C32H72Cl4N6O2
Molecular Weight:714.77
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:Cl.Cl.Cl.Cl.CCCCCCCCCCCCCCCC(=O)NCCCCC(N)C(=O)NCCCNCCCCNCCCN
SMILES:Cl.Cl.Cl.Cl.CCCCCCCCCCCCCCCC(=O)NCCCCC(N)C(=O)NCCCNCCCCNCCCN

(Rac)-AMXT-1501 4HCl is a polyamine transport inhibitor that inhibits polyamine transport and acts synergistically with cisplatin in HNSCC. (Rac)-AMXT-1501 4HCl has potential antimicrobial activity and inhibits neuroblastoma cell proliferation and pneumococcal pod biosynthesis by targeting ornithine decarboxylase and polyamine transport.

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