Name: FBN33428
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HIT ID:HIT218676647
Cas No:
Common Name:FBN33428
alias:Fmoc-Phe-Lys(Boc)-PAB, FBN-33428, FBN33428, FBN 33428
alias:Fmoc-Phe-Lys(Boc)-PAB, FBN-33428, FBN33428, FBN 33428
IUPAC:(9H-fluoren-9-yl)methyl N-{1-[(5-{[(tert-butoxy)carbonyl]amino}-1-{[4-(hydroxymethyl)phenyl]carbamoyl}pentyl)carbamoyl]-2-phenylethyl}carbamate
IUPAC:(9H-fluoren-9-yl)methyl N-{1-[(5-{[(tert-butoxy)carbonyl]amino}-1-{[4-(hydroxymethyl)phenyl]carbamoyl}pentyl)carbamoyl]-2-phenylethyl}carbamate
InChIKey:FSNKYAMDHPYUFM-UHFFFAOYSA-N

Molecular Formula:C42H48N4O7
Molecular Weight:720.867
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:CC(C)(C)OC(=O)NCCCCC(NC(=O)C(Cc1ccccc1)NC(=O)OCC1c2ccccc2-c2ccccc12)C(=O)Nc1ccc(CO)cc1
SMILES:CC(C)(C)OC(=O)NCCCCC(NC(=O)C(Cc1ccccc1)NC(=O)OCC1c2ccccc2-c2ccccc12)C(=O)Nc1ccc(CO)cc1

FBN33428, also referred to as Fmoc-Phe-Lys(Boc)-PAB, is a hydrolyzable linker utilized in the synthesis of antibody-drug conjugates (ADCs). This compound facilitates the creation of hydrolyzable prodrugs, enhancing the targeted delivery of anticancer drugs to metastatic cells.

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