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HIT218678264
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HIT218678264
  • HIT ID:HIT218678264
  • Cas No:2490284-18-7
  • Common Name:KT-531
  • IUPAC:4-[(N-cyclopropyl2,3,4,5-tetrafluorobenzenesulfonamido)methyl]-N-hydroxybenzamide
    IUPAC:4-[(N-cyclopropyl2,3,4,5-tetrafluorobenzenesulfonamido)methyl]-N-hydroxybenzamide
  • InChIKey:HYEWQOQZANKATO-UHFFFAOYSA-N
  • Molecular Formula:C17H14F4N2O4S
  • Molecular Weight:418.36
  • Hydrogen Bond Donor (HBD):
  • Hydrogen Bond Acceptor (HBA):
  • LogP:
  • SMILES:ONC(=O)c1ccc(CN(C2CC2)S(=O)(=O)c2cc(F)c(F)c(F)c2F)cc1
    SMILES:ONC(=O)c1ccc(CN(C2CC2)S(=O)(=O)c2cc(F)c(F)c(F)c2F)cc1
  • KT-531 (KT531) is a highly potent and selective HDAC6 inhibitor with an IC50 value of 8.5 nM and is 39-fold more selective against other HDAC isoenzymes.
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    TargetMolSC
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