Name: Gynosaponin TN2
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HIT ID:HIT218679338
Cas No:
Common Name:Gynosaponin TN2
IUPAC:2-[(6-methyl-2-{7,8,11-trihydroxy-3a,3b,6,6,9a-pentamethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl}hept-5-en-2-yl)oxy]-6-{[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy]methyl}oxane-3,4,5-triol
IUPAC:2-[(6-methyl-2-{7,8,11-trihydroxy-3a,3b,6,6,9a-pentamethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl}hept-5-en-2-yl)oxy]-6-{[(3,4,5-trihydroxy-6-methyloxan-2-yl)oxy]methyl}oxane-3,4,5-triol
InChI key:UWUZNWOONZAPGM-UHFFFAOYSA-N

Molecular Formula:C42H72O13
Molecular Weight:785.025
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:CC1OC(OCC2OC(OC(C)(CCC=C(C)C)C3CCC4(C)C3C(O)CC3C5(C)CC(O)C(O)C(C)(C)C5CCC43C)C(O)C(O)C2O)C(O)C(O)C1O
SMILES:CC1OC(OCC2OC(OC(C)(CCC=C(C)C)C3CCC4(C)C3C(O)CC3C5(C)CC(O)C(O)C(C)(C)C5CCC43C)C(O)C(O)C2O)C(O)C(O)C1O

Gynosaponin TN-2, demonstrating anti-Parkinsonian activity, mitigates L-DOPA (100 and 200 μM)-induced apoptotic cell death in pheochromocytoma 12 cells through the modulation of extracellular signal-regulated protein kinases 1 and 2 activation.

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