Name: 5-HT2 agonist-1
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HIT ID:HIT218695065
Cas No:2708279-78-9
Common Name:5-HT2 agonist-1
IUPAC:3-(2-{[(2-methoxyphenyl)methyl]amino}ethyl)-1-methyl-1H-indol-4-ol hydrochloride
IUPAC:3-(2-{[(2-methoxyphenyl)methyl]amino}ethyl)-1-methyl-1H-indol-4-ol hydrochloride
InChIKey:JDRSVSLEOWVPMA-UHFFFAOYSA-N

Molecular Formula:C19H23ClN2O2
Molecular Weight:346.86
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:Cl.COc1ccccc1CNCCc1cn(C)c2cccc(O)c12
SMILES:Cl.COc1ccccc1CNCCc1cn(C)c2cccc(O)c12

Compound 24, a 5-HT2 agonist-1, selectively activates 5-HT2A, 5-HT2B, and 5-HT2C receptors with IC₅₀ values of 10 nM, 8.3 nM, and 1.6 nM, respectively. The free base form of this compound is utilized in research pertaining to depression, alcoholism, tobacco and cocaine addiction, inflammation, cluster headaches, PTSD, seizure disorders, and additional CNS disorders ^[1].

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