Name: BMS-986104
Rating: 4 (6 reviews)

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HIT ID:HIT218695920
Cas No:1622180-31-7
Common Name:BMS-986104
IUPAC:[(1R,3S)-1-amino-3-[(6R)-6-hexyl-5,6,7,8-tetrahydronaphthalen-2-yl]cyclopentyl]methanol
IUPAC:[(1R,3S)-1-amino-3-[(6R)-6-hexyl-5,6,7,8-tetrahydronaphthalen-2-yl]cyclopentyl]methanol
InChI key:BPMMYKAHRIEVDH-VOQZNFBZSA-N

Molecular Formula:C22H35NO
Molecular Weight:329.528
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:CCCCCC[C@@H]1CCc2cc(ccc2C1)[C@H]1CC[C@](N)(CO)C1
SMILES:CCCCCC[C@@H]1CCc2cc(ccc2C1)[C@H]1CC[C@](N)(CO)C1

BMS-986104 is an effective selective modulator of the S1P1 receptor. It demonstrates efficacy in the mouse EAE model, comparable to that of FTY720. Furthermore, BMS-986104 shows promising remyelination properties in three-dimensional brain cell cultures subjected to lysophosphatidylcholine (LPC)-induced demyelination.

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