Name: Z-Gly-Gly-Arg-AMC
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HIT ID:HIT218697911
Cas No:66216-78-2
Common Name:Z-Gly-Gly-Arg-AMC
IUPAC:benzyl N-{[({[(1S)-4-carbamimidamido-1-[(4-methyl-2-oxo-2H-chromen-7-yl)carbamoyl]butyl]carbamoyl}methyl)carbamoyl]methyl}carbamate
IUPAC:benzyl N-{[({[(1S)-4-carbamimidamido-1-[(4-methyl-2-oxo-2H-chromen-7-yl)carbamoyl]butyl]carbamoyl}methyl)carbamoyl]methyl}carbamate
InChI key:SXTGIAYWYXVNLT-NRFANRHFSA-N

Molecular Formula:C28H33N7O7
Molecular Weight:579.614
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:Cc1cc(=O)oc2cc(NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)CNC(=O)OCc3ccccc3)ccc12
SMILES:Cc1cc(=O)oc2cc(NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)CNC(=O)OCc3ccccc3)ccc12

Z-Gly-Gly-Arg-AMC is a specific fluorogenic substrate used to assess thrombin generation and thrombin activity in Platelet-Rich Plasma (PRP) and Platelet-Poor Plasma (PPP).

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