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HIT218698030
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HIT218698030
HIT ID:
HIT218698030
Cas No:
327177-34-4
Common Name:
tcY-NH2
IUPAC:
(2S)-6-amino-N-[(1S)-1-carbamoyl-2-phenylethyl]-2-(2-{[(2S)-1-[(2S)-3-(4-hydroxyphenyl)-2-[(2E)-3-phenylprop-2-enamido]propanoyl]pyrrolidin-2-yl]formamido}acetamido)hexanamide
IUPAC:
(2S)-6-amino-N-[(1S)-1-carbamoyl-2-phenylethyl]-2-(2-{[(2S)-1-[(2S)-3-(4-hydroxyphenyl)-2-[(2E)-3-phenylprop-2-enamido]propanoyl]pyrrolidin-2-yl]formamido}acetamido)hexanamide
InChIKey:
XKRAKQXQVIGYQC-PHOSSJRVSA-N
Molecular Formula:
C40H49N7O7
Molecular Weight:
739.874
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:
NCCCC[C@H](NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(O)cc1)NC(=O)\C=C\c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
SMILES:
NCCCC[C@H](NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(O)cc1)NC(=O)\C=C\c1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Selective PAR4 antagonist peptide. Inhibits endostatin release and platelet aggregation induced by thrombin.
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