Name: PF-07038124 HCl
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HIT ID:HIT218700792
Cas No:2415317-57-4
Common Name:PF-07038124 HCl
alias:PF-07038124 HCl(2415085-44-6 Free base)
IUPAC:(4R)-4-[5-(4-methoxy-3-propoxyphenyl)pyridin-3-yl]-1,2-oxaborolan-2-ol hydrochloride
IUPAC:(4R)-4-[5-(4-methoxy-3-propoxyphenyl)pyridin-3-yl]-1,2-oxaborolan-2-ol hydrochloride
InChIKey:QHNSQBUGQNRYBR-NTISSMGPSA-N

Molecular Formula:C18H23BClNO4
Molecular Weight:363.65
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:Cl.CCCOc1cc(ccc1OC)-c1cncc(c1)[C@@H]1COB(O)C1
SMILES:Cl.CCCOc1cc(ccc1OC)-c1cncc(c1)[C@@H]1COB(O)C1

PF-07038124 HCl is a selective and potent PDE4 inhibitor with an IC₅₀ of 0.5 nM for PDE4B2.PF-07038124 HCl inhibits IL-13, IL-4, and IFNγ, and can be used in the study of skin disorders such as atopic dermatitis and plaque psoriasis.

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