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  3. HIT218832565
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HIT218832565
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HIT218832565
  • HIT ID:HIT218832565
  • Cas No:
  • 常用名:N-5-Carboxypentyl-1-deoxynojirimycin
    常用名:N-5-Carboxypentyl-1-deoxynojirimycin
  • 别名:N-5-Carboxypentyl-1-dNM, N-5-Carboxypentyl-1-DNJ
    别名:N-5-Carboxypentyl-1-dNM, N-5-Carboxypentyl-1-DNJ
  • IUPAC:6-[3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]hexanoic acid
    IUPAC:6-[3,4,5-trihydroxy-2-(hydroxymethyl)piperidin-1-yl]hexanoic acid
  • InChI key:KTNVTDIFZTZBJY-UHFFFAOYSA-N
  • 分子式:C12H23NO6
  • 分子量:277.317
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:OCC1C(O)C(O)C(O)CN1CCCCCC(O)=O
    SMILES:OCC1C(O)C(O)C(O)CN1CCCCCC(O)=O
  • 1-Deoxynojirimycin, a potent glucose analog, inhibits α-glucosidase I and II effectively. Its derivative, N-5-Carboxypentyl-1-deoxynojirimycin, serves as a ligand for glucosidase I and II purification, utilizing carboxypentyl groups for affinity chromatography resin linkage. Furthermore, N-5-Carboxypentyl-1-deoxynojirimycin demonstrates comparable or superior inhibition of glucosidase compared to 1-deoxynojirimycin, with inhibition constants (Ki) of 0.45 µM and 2.1 µM, respectively, for pig liver glucosidase I.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
    纯度
    -
    ¥ 1,120.00
    1

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