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HIT218832581
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HIT218832581
  • HIT ID:HIT218832581
  • Cas No:
  • 常用名:Tafluprost ethyl ester
  • 别名:AFP 175
  • IUPAC:ethyl 7-[2-(3,3-difluoro-4-phenoxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl]hept-5-enoate
    IUPAC:ethyl 7-[2-(3,3-difluoro-4-phenoxybut-1-en-1-yl)-3,5-dihydroxycyclopentyl]hept-5-enoate
  • InChI key:SPWJIEVPQKMQPO-UHFFFAOYSA-N
  • 分子式:C24H32F2O5
  • 分子量:438.512
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CCOC(=O)CCCC=CCC1C(O)CC(O)C1C=CC(F)(F)COc1ccccc1
    SMILES:CCOC(=O)CCCC=CCC1C(O)CC(O)C1C=CC(F)(F)COc1ccccc1
  • Tafluprost, an analog of prostaglandin F2α (PGF2α) that primarily targets the FP receptor, is employed in glaucoma treatment. Tafluprost (free acid) serves as a potent FP receptor agonist with a Ki value of 0.4 nM. Its derivative, tafluprost ethyl ester, potentially offers enhanced lipid solubility relative to its free acid form, possibly leading to superior tissue absorption and reduced effective concentration requirements.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
    纯度
    -
    ¥ 1,720.00
    1

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