Name: Δ7(Z)-C14-HSL
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HIT ID:HIT218832585
Cas No:
Common Name:Δ7(Z)-C14-HSL
alias:N-(3-Oxo-7Z-tetradecenoyl)-L-homoserine lactone
alias:N-(3-Oxo-7Z-tetradecenoyl)-L-homoserine lactone
IUPAC:3-oxo-N-(2-oxooxolan-3-yl)tetradec-7-enamide
IUPAC:3-oxo-N-(2-oxooxolan-3-yl)tetradec-7-enamide
InChI key:MGGGOCSKDLGISA-UHFFFAOYSA-N

Molecular Formula:C18H29NO4
Molecular Weight:323.433
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:CCCCCCC=CCCCC(=O)CC(=O)NC1CCOC1=O
SMILES:CCCCCCC=CCCCC(=O)CC(=O)NC1CCOC1=O

Δ7(Z)-C14-HSL (Compound 12), an immunosuppressive agent, inhibits the proliferation of mouse splenic cells, exhibiting an IC 50 of 17 μM. It holds promise for exploring its role as a molecular mechanism in TNF-R-driven immune diseases, including autoimmune disorders like psoriasis, rheumatoid arthritis, and type 1 diabetes [1].

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