Name: 15(R)-15-methyl Prostaglandin A2
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HIT ID:HIT218832614
Cas No:
Common Name:15(R)-15-methyl Prostaglandin A2
Common Name:15(R)-15-methyl Prostaglandin A2
alias:15(R)-15-methyl PGA2
IUPAC:7-[2-(3-hydroxy-3-methyloct-1-en-1-yl)-5-oxocyclopent-3-en-1-yl]hept-5-enoic acid
IUPAC:7-[2-(3-hydroxy-3-methyloct-1-en-1-yl)-5-oxocyclopent-3-en-1-yl]hept-5-enoic acid
InChI key:UEBXYYKXJUBAJX-UHFFFAOYSA-N

Molecular Formula:C21H32O4
Molecular Weight:348.483
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:CCCCCC(C)(O)C=CC1C=CC(=O)C1CC=CCCCC(O)=O
SMILES:CCCCCC(C)(O)C=CC1C=CC(=O)C1CC=CCCCC(O)=O

Arbaprostil, a synthetic analog of prostaglandin E2 (PGE2) known as 15(R)-15-methyl prostaglandin E2, was developed for its cytoprotective activity. In the commercial production of bulk arbaprostil, one potential impurity is 15(R)-15-methyl Prostaglandin A2 (15(R)-15-methyl PGA2). The pharmacology and EP receptor binding affinity of 15(R)-15-methyl PGA2 have not been reported.

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