Name: 9-keto Fluprostenol isopropyl ester
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT218832653
Cas No:
常用名:9-keto Fluprostenol isopropyl ester
常用名:9-keto Fluprostenol isopropyl ester
IUPAC:propan-2-yl 7-(3-hydroxy-2-{3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}-5-oxocyclopentyl)hept-5-enoate
IUPAC:propan-2-yl 7-(3-hydroxy-2-{3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}-5-oxocyclopentyl)hept-5-enoate
InChI key:OKXNVRDMSRTJEN-UHFFFAOYSA-N

分子式:C26H33F3O6
分子量:498.539
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CC(C)OC(=O)CCCC=CCC1C(C=CC(O)COc2cccc(c2)C(F)(F)F)C(O)CC1=O
SMILES:CC(C)OC(=O)CCCC=CCC1C(C=CC(O)COc2cccc(c2)C(F)(F)F)C(O)CC1=O

9-Keto Fluprostenol Isopropyl Ester, an ester derivative of the FP receptor agonist fluprostenol, undergoes oxidation at carbon 9. This compound serves as a potential prodrug for 9-keto fluprostenol, which may function as an agonist at EP receptors. Additionally, it is considered a possible metabolite of fluprostenol isopropyl ester (travoprost), drawing parallels to the metabolism of latanoprost by 15-hydroxyprostaglandin dehydrogenase observed in monkey cornea. Furthermore, certain F-series prostaglandins, such as 6-keto prostaglandin F1α (PGF1α), undergo conversion to their E-series counterparts in isolated human platelets, highlighting a metabolic pathway of relevance.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~