Name: 11(S)-HETE
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HIT ID:HIT218832657
Cas No:
Common Name:11(S)-HETE
alias:11(S)-Hydroxyeicosatetraenoic Acid
IUPAC:11-hydroxyicosa-5,8,12,14-tetraenoic acid
IUPAC:11-hydroxyicosa-5,8,12,14-tetraenoic acid
InChIKey:GCZRCCHPLVMMJE-UHFFFAOYSA-N

Molecular Formula:C20H32O3
Molecular Weight:320.473
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:CCCCCC=CC=CC(O)CC=CCC=CCCCC(O)=O
SMILES:CCCCCC=CC=CC(O)CC=CCC=CCCCC(O)=O

11(S)-HETE, an (S) enantiomer of 11(R)-HETE and a type of oxylipin, is non-enzymatically synthesized from arachidonic acid. Compared to its counterpart, 11(S)-HETE levels are found to be elevated in both isolated human plasma and serum, as well as in LPS-stimulated isolated human plasma. Notably, patients with allergic rhinitis exhibit a decrease in 11(S)-HETE levels in their serum following one year of double-mite subcutaneous immunotherapy (DM-SCIT), correlating with an enhanced quality of life, particularly in aspects related to rhinoconjunctivitis.

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