Name: 11β-Prostaglandin F2α Ethanolamide
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HIT ID:HIT218832664
Cas No:
Common Name:11β-Prostaglandin F2α Ethanolamide
Common Name:11β-Prostaglandin F2α Ethanolamide
alias:11-epi PGF2α-EA
IUPAC:7-[3,5-dihydroxy-2-(3-hydroxyoct-1-en-1-yl)cyclopentyl]-N-(2-hydroxyethyl)hept-5-enamide
IUPAC:7-[3,5-dihydroxy-2-(3-hydroxyoct-1-en-1-yl)cyclopentyl]-N-(2-hydroxyethyl)hept-5-enamide
InChI key:XCVCLIRZZCGEMU-UHFFFAOYSA-N

Molecular Formula:C22H39NO5
Molecular Weight:397.556
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:CCCCCC(O)C=CC1C(O)CC(O)C1CC=CCCCC(=O)NCCO
SMILES:CCCCCC(O)C=CC1C(O)CC(O)C1CC=CCCCC(=O)NCCO

11β-Prostaglandin F2αethanolamide (11β-PGF2α-EA), posited as the hepatic metabolite derived from PGD2-EA during COX-2 metabolism of AEA—an endogenous cannabinoid present in brain, liver, and various mammalian tissues—is synthesized directly from AEA via COX-2 and specific prostaglandin synthase, leading to ethanolamide versions of classical prostaglandins. Additionally, PGD2-EA formation occurs in activated RAW 264.7 cells upon AEA treatment.

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