Name: Lentztrehalose B
Rating: 4 (6 reviews)

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HIT ID:HIT218832668
Cas No:
Common Name:Lentztrehalose B
IUPAC:2-{[3,4-dihydroxy-6-(hydroxymethyl)-5-[(3-methylbut-2-en-1-yl)oxy]oxan-2-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
IUPAC:2-{[3,4-dihydroxy-6-(hydroxymethyl)-5-[(3-methylbut-2-en-1-yl)oxy]oxan-2-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
InChI key:NODZOHVOYATRLP-UHFFFAOYSA-N

Molecular Formula:C17H30O11
Molecular Weight:410.416
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:CC(C)=CCOC1C(CO)OC(OC2OC(CO)C(O)C(O)C2O)C(O)C1O
SMILES:CC(C)=CCOC1C(CO)OC(OC2OC(CO)C(O)C(O)C2O)C(O)C1O

Lentztrehalose B, a microbial disaccharide metabolite isolated from Lentzea, exhibits a range of biological activities. At a concentration of 100 µM, it demonstrates antioxidant properties in an oxygen radical absorbance capacity (ORAC) assay. Furthermore, Lentztrehalose B at 10 mM inhibits porcine kidney trehalase, an enzyme involved in trehalose metabolism. Additionally, it induces autophagy in MeWo melanoma and OVK18 ovarian cancer cells when applied at 100 mM.

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