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HIT218832668
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HIT218832668
  • HIT ID:HIT218832668
  • Cas No:
  • 常用名:Lentztrehalose B
  • IUPAC:2-{[3,4-dihydroxy-6-(hydroxymethyl)-5-[(3-methylbut-2-en-1-yl)oxy]oxan-2-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
    IUPAC:2-{[3,4-dihydroxy-6-(hydroxymethyl)-5-[(3-methylbut-2-en-1-yl)oxy]oxan-2-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
  • InChI key:NODZOHVOYATRLP-UHFFFAOYSA-N
  • 分子式:C17H30O11
  • 分子量:410.416
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CC(C)=CCOC1C(CO)OC(OC2OC(CO)C(O)C(O)C2O)C(O)C1O
    SMILES:CC(C)=CCOC1C(CO)OC(OC2OC(CO)C(O)C(O)C2O)C(O)C1O
  • Lentztrehalose B, a microbial disaccharide metabolite isolated from Lentzea, exhibits a range of biological activities. At a concentration of 100 µM, it demonstrates antioxidant properties in an oxygen radical absorbance capacity (ORAC) assay. Furthermore, Lentztrehalose B at 10 mM inhibits porcine kidney trehalase, an enzyme involved in trehalose metabolism. Additionally, it induces autophagy in MeWo melanoma and OVK18 ovarian cancer cells when applied at 100 mM.
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