Name: RCB-02-4-8
Rating: 4 (6 reviews)

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HIT ID:HIT218832679
Cas No:
Common Name:RCB-02-4-8
IUPAC:12-{[(non-2-yn-1-yloxy)carbonyl]oxy}octadec-9-en-1-yl 3-{[2-(diethylamino)ethyl]({3-[(12-{[(non-2-yn-1-yloxy)carbonyl]oxy}octadec-9-en-1-yl)oxy]-3-oxopropyl})amino}propanoate
IUPAC:12-{[(non-2-yn-1-yloxy)carbonyl]oxy}octadec-9-en-1-yl 3-{[2-(diethylamino)ethyl]({3-[(12-{[(non-2-yn-1-yloxy)carbonyl]oxy}octadec-9-en-1-yl)oxy]-3-oxopropyl})amino}propanoate
InChIKey:ZPIXBWGMGBPXDA-UHFFFAOYSA-N

Molecular Formula:C68H120N2O10
Molecular Weight:1125.712
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:CCCCCCC#CCOC(=O)OC(CCCCCC)CC=CCCCCCCCCOC(=O)CCN(CCN(CC)CC)CCC(=O)OCCCCCCCCC=CCC(CCCCCC)OC(=O)OCC#CCCCCCC
SMILES:CCCCCCC#CCOC(=O)OC(CCCCCC)CC=CCCCCCCCCOC(=O)CCN(CCN(CC)CC)CCC(=O)OCCCCCCCCC=CCC(CCCCCC)OC(=O)OCC#CCCCCCC

RCB-02-4-8, an ionizable cationic lipid designed for the formulation of lipid nanoparticles (LNPs), enhances mRNA delivery with proven effectiveness in increasing lung transfection efficiency in mice ^[1].

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