Name: PBD dimer-2
Rating: 4 (6 reviews)

In Stock

SDF File

Edit Structure

Find Similar

HIT ID:HIT218832703
Cas No:
Common Name:PBD dimer-2
IUPAC:13-methoxy-12-{[5-({13-methoxy-2-oxo-3,9-diazatricyclo[8.4.0.0^{3,7}]tetradeca-1(14),8,10,12-tetraen-12-yl}oxy)pentyl]oxy}-3,9-diazatricyclo[8.4.0.0^{3,7}]tetradeca-1(10),8,11,13-tetraen-2-one
IUPAC:13-methoxy-12-{[5-({13-methoxy-2-oxo-3,9-diazatricyclo[8.4.0.0^{3,7}]tetradeca-1(14),8,10,12-tetraen-12-yl}oxy)pentyl]oxy}-3,9-diazatricyclo[8.4.0.0^{3,7}]tetradeca-1(10),8,11,13-tetraen-2-one
InChI key:JMRUKTNVBSHJFI-UHFFFAOYSA-N

Molecular Formula:C31H36N4O6
Molecular Weight:560.651
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:COc1cc2c(cc1OCCCCCOc1cc3N=CC4CCCN4C(=O)c3cc1OC)N=CC1CCCN1C2=O
SMILES:COc1cc2c(cc1OCCCCCOc1cc3N=CC4CCCN4C(=O)c3cc1OC)N=CC1CCCN1C2=O

PBD dimer-2 (compound 2c), a C8-linked pyrrolobenzodiazepine dimer, has the capability to span an extra base pair and cross-link the 5′-Pu-GA(T/A)TC-Py sequence. It serves as a potential payload for antibody–agent conjugates (ADCs) and is under research for cancer treatments [1] [2].

Marketplace OffersShowing from 1 suppliers

You cannot determine which compound library is the best fit for your project? Do you need a custom solution? AnyMol is always ready to help you.

：400-820-0310

Loading ~