Name: DIBAC-GGFG-NH2CH2-Dxd
Rating: 4 (6 reviews)

In Stock

SDF File

Edit Structure

Find Similar

* 凭借在化合物合成方面的丰富经验，我们可以根据您的研究需求为该产品提供快速定制合成服务。

HIT ID:HIT218832704
Cas No:
Common Name:DIBAC-GGFG-NH2CH2-Dxd
IUPAC:4-{2-azatricyclo[10.4.0.0^{4,9}]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-N-[({[(1-{[({[({10-ethyl-18-fluoro-10-hydroxy-19-methyl-5,9-dioxo-8-oxa-4,15-diazahexacyclo[14.7.1.0^{2,14}.0^{4,13}.0^{6,11}.0^{20,24}]tetracosa-1,6(11),12,14,16,18,20(24)-heptaen-23-yl}carbamoyl)methoxy]methyl}carbamoyl)methyl]carbamoyl}-2-phenylethyl)carbamoyl]methyl}carbamoyl)methyl]-4-oxobutanamide
IUPAC:4-{2-azatricyclo[10.4.0.0^{4,9}]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-N-[({[(1-{[({[({10-ethyl-18-fluoro-10-hydroxy-19-methyl-5,9-dioxo-8-oxa-4,15-diazahexacyclo[14.7.1.0^{2,14}.0^{4,13}.0^{6,11}.0^{20,24}]tetracosa-1,6(11),12,14,16,18,20(24)-heptaen-23-yl}carbamoyl)methoxy]methyl}carbamoyl)methyl]carbamoyl}-2-phenylethyl)carbamoyl]methyl}carbamoyl)methyl]-4-oxobutanamide
InChIKey:HXQAFVZJVFQLRZ-UHFFFAOYSA-N

Molecular Formula:C61H58FN9O12
Molecular Weight:1128.184
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:CCC1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)c5CCC(NC(=O)COCNC(=O)CNC(=O)C(Cc6ccccc6)NC(=O)CNC(=O)CNC(=O)CCC(=O)N6Cc7ccccc7C#Cc7ccccc67)c(c3Cn1c2=O)c45
SMILES:CCC1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)c5CCC(NC(=O)COCNC(=O)CNC(=O)C(Cc6ccccc6)NC(=O)CNC(=O)CNC(=O)CCC(=O)N6Cc7ccccc7C#Cc7ccccc67)c(c3Cn1c2=O)c45

DIBAC-GGFG-NH2CH2-Dxd (compound LP4), a derivative of Camptothecin, serves as a linker-payload for protein-agent conjugates ^[1]. It is utilized as a payload in the antibody-coupling drug ADC (DS-8201a). Additionally, this compound functions as a click chemistry reagent due to its DBCO group, facilitating strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-group-containing molecules.

Marketplace OffersShowing from 1 suppliers

You cannot determine which compound library is the best fit for your project? Do you need a custom solution? AnyMol is always ready to help you.

：400-820-0310

Loading ~