Name: Pomalidomide 4'-alkylC6-azide
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HIT ID:HIT218832803
Cas No:
Common Name:Pomalidomide 4'-alkylC6-azide
alias:Pomalidomide 4'-alkylC6-azide, HUN-55727, HUN55727, HUN 55727
alias:Pomalidomide 4'-alkylC6-azide, HUN-55727, HUN55727, HUN 55727
IUPAC:4-[(6-azidohexyl)amino]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
IUPAC:4-[(6-azidohexyl)amino]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
InChIKey:HIFBXUYLIWPOBR-UHFFFAOYSA-N

Molecular Formula:C19H22N6O4
Molecular Weight:398.423
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:[N-]=[N+]=NCCCCCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
SMILES:[N-]=[N+]=NCCCCCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12

Pomalidomide 4'-alkylC6-azide, a Pomalidomide-based cereblon (CRBN) ligand, facilitates the recruitment of CRBN protein. It is designed to attach to a protein through a linker, enabling the formation of PROTAC [1].

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