Name: Lenalidomide 4'-PEG2-azide
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HIT ID:HIT218832804
Cas No:
Common Name:Lenalidomide 4'-PEG2-azide
alias:PUN-55480, PUN55480, PUN 55480, Lenalidomide 4'-PEG2-azide
alias:PUN-55480, PUN55480, PUN 55480, Lenalidomide 4'-PEG2-azide
IUPAC:3-[4-({2-[2-(2-azidoethoxy)ethoxy]ethyl}amino)-1-oxo-2,3-dihydro-1H-isoindol-2-yl]piperidine-2,6-dione
IUPAC:3-[4-({2-[2-(2-azidoethoxy)ethoxy]ethyl}amino)-1-oxo-2,3-dihydro-1H-isoindol-2-yl]piperidine-2,6-dione
InChIKey:PUCMLUIGSAMTJO-UHFFFAOYSA-N

Molecular Formula:C19H24N6O5
Molecular Weight:416.438
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:[N-]=[N+]=NCCOCCOCCNc1cccc2C(=O)N(Cc12)C1CCC(=O)NC1=O
SMILES:[N-]=[N+]=NCCOCCOCCNc1cccc2C(=O)N(Cc12)C1CCC(=O)NC1=O

Lenalidomide 4'-PEG2-azide, a Lenalidomide-derived Cereblon ligand, facilitates the recruitment of CRBN protein. This compound can be tethered via a linker to a protein ligand, enabling the formation of PROTAC [1].

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