Name: FHT-2344
Rating: 4 (6 reviews)

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HIT ID:HIT218832808
Cas No:
Common Name:FHT-2344
IUPAC:2-[(1-methanesulfonyl-1H-pyrrol-3-yl)formamido]-3-methoxy-N-{4-[3-(1-methyl-1H-pyrazol-3-yl)phenyl]-1,3-thiazol-2-yl}propanamide
IUPAC:2-[(1-methanesulfonyl-1H-pyrrol-3-yl)formamido]-3-methoxy-N-{4-[3-(1-methyl-1H-pyrazol-3-yl)phenyl]-1,3-thiazol-2-yl}propanamide
InChIKey:APLVGTKXOIMODQ-UHFFFAOYSA-N

Molecular Formula:C23H24N6O5S2
Molecular Weight:528.6
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:COCC(NC(=O)c1ccn(c1)S(C)(=O)=O)C(=O)Nc1nc(cs1)-c1cccc(c1)-c1ccn(C)n1
SMILES:COCC(NC(=O)c1ccn(c1)S(C)(=O)=O)C(=O)Nc1nc(cs1)-c1cccc(c1)-c1ccn(C)n1

FHT-2344, a SMARCA4/SMARCA2 ATPase inhibitor, exhibits anticancer activity with half-maximal inhibitory concentrations (IC 50 ) of 0.026 μM for SMARCA4 and 0.013 μM for SMARCA2, respectively [1].

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