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  3. HIT218832826
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HIT218832826
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HIT218832826
  • HIT ID:HIT218832826
  • Cas No:
  • 常用名:α-Cortolone
  • 别名:20α-Cortolone
  • IUPAC:1-(1,2-dihydroxyethyl)-1,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-10-one
    IUPAC:1-(1,2-dihydroxyethyl)-1,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-10-one
  • InChI key:JXCOSKURGJMQSG-UHFFFAOYSA-N
  • 分子式:C21H34O5
  • 分子量:366.498
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:CC12CC(=O)C3C(CCC4CC(O)CCC34C)C1CCC2(O)C(O)CO
    SMILES:CC12CC(=O)C3C(CCC4CC(O)CCC34C)C1CCC2(O)C(O)CO
  • α-Cortolone, a metabolite of the glucocorticoid cortisol (hydrocortisone), is produced through the action of 20α-hydroxysteroid dehydrogenase (20α-HSD) via a tetrahydrocortisone (THE) intermediate. Studies indicate that urinary levels of α-cortolone are reduced in patients experiencing severe anorexia nervosa and postmenopausal women diagnosed with endometrial adenocarcinoma, in comparison to postmenopausal women without the condition.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    35日内发货
    纯度
    -
    ¥ 5,550.00
    1

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