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HIT218832826
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HIT218832826
  • HIT ID:HIT218832826
  • Cas No:
  • Common Name:α-Cortolone
  • alias:20α-Cortolone
  • IUPAC:1-(1,2-dihydroxyethyl)-1,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-10-one
    IUPAC:1-(1,2-dihydroxyethyl)-1,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-10-one
  • InChIKey:JXCOSKURGJMQSG-UHFFFAOYSA-N
  • Molecular Formula:C21H34O5
  • Molecular Weight:366.498
  • Hydrogen Bond Donor (HBD):
  • Hydrogen Bond Acceptor (HBA):
  • LogP:
  • SMILES:CC12CC(=O)C3C(CCC4CC(O)CCC34C)C1CCC2(O)C(O)CO
    SMILES:CC12CC(=O)C3C(CCC4CC(O)CCC34C)C1CCC2(O)C(O)CO
  • α-Cortolone, a metabolite of the glucocorticoid cortisol (hydrocortisone), is produced through the action of 20α-hydroxysteroid dehydrogenase (20α-HSD) via a tetrahydrocortisone (THE) intermediate. Studies indicate that urinary levels of α-cortolone are reduced in patients experiencing severe anorexia nervosa and postmenopausal women diagnosed with endometrial adenocarcinoma, in comparison to postmenopausal women without the condition.
Marketplace OffersShowing from 1 suppliers
  • Supplier
    TargetMolSC
    Pack Size
    Estimated Lead Time
    35 days
    Purity
    -
    $ 793.00
    1

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