Name: 5-Androstenetriol
Rating: 5 (10 reviews)

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HIT ID:HIT218832828
Cas No:
常用名:5-Androstenetriol
别名:Δ5-AT
IUPAC:9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-1,2,7-triol
IUPAC:9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-1,2,7-triol
InChI key:GUGSXATYPSGVAY-UHFFFAOYSA-N

分子式:C19H30O3
分子量:306.446
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CC12CCC3C(CC=C4CC(O)CCC34C)C1CC(O)C2O
SMILES:CC12CCC3C(CC=C4CC(O)CCC34C)C1CC(O)C2O

5-Androstenetriol, a steroid and active metabolite of dehydroepiandrosterone (DHEA), demonstrates significant therapeutic effects. Administered at 0.75 mg/25 g body weight, it mitigates radiation-induced mortality and facilitates hematopoietic recovery from surviving stem cells in mice. Moreover, a dosage of 40 mg/kg enhances survival rates in rats subjected to surgical trauma-induced sepsis. Additionally, elevated urinary levels of 5-androstenetriol are observed in women suffering from androgenic alopecia.

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