Name: Bassianin
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HIT ID:HIT218832847
Cas No:
Common Name:Bassianin
IUPAC:3-(6,8-dimethyldeca-2,4,6-trienoyl)-1,4-dihydroxy-5-(4-hydroxyphenyl)-1,2-dihydropyridin-2-one
IUPAC:3-(6,8-dimethyldeca-2,4,6-trienoyl)-1,4-dihydroxy-5-(4-hydroxyphenyl)-1,2-dihydropyridin-2-one
InChI key:LJUJZTYMRBJWDZ-UHFFFAOYSA-N

Molecular Formula:C23H25NO5
Molecular Weight:395.455
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:CCC(C)C=C(C)C=CC=CC(=O)c1c(O)c(cn(O)c1=O)-c1ccc(O)cc1
SMILES:CCC(C)C=C(C)C=CC=CC(=O)c1c(O)c(cn(O)c1=O)-c1ccc(O)cc1

Bassianin, a fungal metabolite identified in Beauveria, demonstrates inhibition of Mg2+-, Ca2+-, and Na+/K+-ATPase activities in equine erythrocyte ghosts, with inhibition rates of 81%, 58%, and 23%, respectively, at a concentration of 200 µg/ml. Additionally, bassianin exhibits cytotoxic properties against Sf9 and Sf21 insect cells, with 50% cytotoxic concentration (CC50) values of 4.91 µM and 12.12 µM, respectively.

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