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HIT218832864
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HIT218832864
  • HIT ID:HIT218832864
  • Cas No:
  • Common Name:Streptimidone
  • alias:NSC 66645, Ao58A
  • IUPAC:4-(2-hydroxy-5,7-dimethyl-4-oxonona-6,8-dien-1-yl)piperidine-2,6-dione
    IUPAC:4-(2-hydroxy-5,7-dimethyl-4-oxonona-6,8-dien-1-yl)piperidine-2,6-dione
  • InChIKey:ZRYKVDWGQVQRPG-UHFFFAOYSA-N
  • Molecular Formula:C16H23NO4
  • Molecular Weight:293.363
  • Hydrogen Bond Donor (HBD):
  • Hydrogen Bond Acceptor (HBA):
  • LogP:
  • SMILES:CC(C=C(C)C=C)C(=O)CC(O)CC1CC(=O)NC(=O)C1
    SMILES:CC(C=C(C)C=C)C(=O)CC(O)CC1CC(=O)NC(=O)C1
  • Streptimidone, a metabolite produced by Streptomyces, exhibits various biological activities, including inhibiting protein synthesis at 50 µg/ml in cell-free assays and reducing tumor growth in rat xenograft models of H.S. No. 1 human sarcoma and H.Ep. No. 3 human epidermoid carcinoma at daily doses of 12.5 and 25 mg/kg.
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