Name: Streptimidone
Rating: 5 (10 reviews)

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sdf 文件

结构编辑

类似物检索

HIT ID:HIT218832864
Cas No:
常用名:Streptimidone
别名:NSC 66645, Ao58A
IUPAC:4-(2-hydroxy-5,7-dimethyl-4-oxonona-6,8-dien-1-yl)piperidine-2,6-dione
IUPAC:4-(2-hydroxy-5,7-dimethyl-4-oxonona-6,8-dien-1-yl)piperidine-2,6-dione
InChI key:ZRYKVDWGQVQRPG-UHFFFAOYSA-N

分子式:C16H23NO4
分子量:293.363
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CC(C=C(C)C=C)C(=O)CC(O)CC1CC(=O)NC(=O)C1
SMILES:CC(C=C(C)C=C)C(=O)CC(O)CC1CC(=O)NC(=O)C1

Streptimidone, a metabolite produced by Streptomyces, exhibits various biological activities, including inhibiting protein synthesis at 50 µg/ml in cell-free assays and reducing tumor growth in rat xenograft models of H.S. No. 1 human sarcoma and H.Ep. No. 3 human epidermoid carcinoma at daily doses of 12.5 and 25 mg/kg.

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