Name: Yhhu-3792 hydrochloride
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HIT ID:HIT218832976
Cas No:
Common Name:Yhhu-3792 hydrochloride
IUPAC:5-(3-methoxyphenoxy)-N2-[4-(propan-2-yl)phenyl]quinazoline-2,4-diamine hydrochloride
IUPAC:5-(3-methoxyphenoxy)-N2-[4-(propan-2-yl)phenyl]quinazoline-2,4-diamine hydrochloride
InChIKey:WNNJMAWCEOKXEJ-UHFFFAOYSA-N

Molecular Formula:C24H25ClN4O2
Molecular Weight:436.94
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:Cl.COc1cccc(Oc2cccc3nc(Nc4ccc(cc4)C(C)C)nc(N)c23)c1
SMILES:Cl.COc1cccc(Oc2cccc3nc(Nc4ccc(cc4)C(C)C)nc(N)c23)c1

Yhhu-3792 hydrochloride is a compound that bolsters the self-renewal capacity of neural stem cells (NSCs), catalyzes the Notch signaling pathway, and upregulates expression of Hes3 and Hes5. It augments the NSC pool, stimulates endogenous neurogenesis in the mouse hippocampal dentate gyrus (DG), and enhances mice's spatial and episodic memory skills. This compound shows promise for researching learning and memory impairments linked to DG dysfunction [1].

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