Name: TS-24
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HIT ID:HIT218833041
Cas No:1563260-97-8
Common Name:TS-24
alias:TS24, TS 24
IUPAC:1-(1-benzofuran-2-yl)-3-(1-methyl-1H-indol-3-yl)prop-2-en-1-one
IUPAC:1-(1-benzofuran-2-yl)-3-(1-methyl-1H-indol-3-yl)prop-2-en-1-one
InChIKey:XJDLZSTZQYVHKL-UHFFFAOYSA-N

Molecular Formula:C20H15NO2
Molecular Weight:301.345
Hydrogen Bond Donor (HBD):
Hydrogen Bond Acceptor (HBA):
LogP:
SMILES:Cn1cc(C=CC(=O)c2cc3ccccc3o2)c2ccccc12
SMILES:Cn1cc(C=CC(=O)c2cc3ccccc3o2)c2ccccc12

TS-24 is an inhibitor of the cysteine protease histatin S (CTSS).TS-24 promotes BRCA1-mediated apoptosis and shows radiosensitization in a TNBC xenograft mouse model.

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