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  3. HIT218848436
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HIT218848436
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HIT218848436
  • HIT ID:HIT218848436
  • Cas No:2922826-56-8
  • 常用名:MA220607
  • IUPAC:2-(4-tert-butylphenyl)-4-[(1E)-2-(4-tert-butylphenyl)ethenyl]-1-methyl-5-phenylpyridin-1-ium iodide
    IUPAC:2-(4-tert-butylphenyl)-4-[(1E)-2-(4-tert-butylphenyl)ethenyl]-1-methyl-5-phenylpyridin-1-ium iodide
  • InChI key:PETRXUJAJSDTOF-ZUQRMPMESA-M
  • 分子式:C34H38IN
  • 分子量:587.589
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:[I-].C[n+]1cc(c(\C=C\c2ccc(cc2)C(C)(C)C)cc1-c1ccc(cc1)C(C)(C)C)-c1ccccc1
    SMILES:[I-].C[n+]1cc(c(\C=C\c2ccc(cc2)C(C)(C)C)cc1-c1ccc(cc1)C(C)(C)C)-c1ccccc1
  • MA220607 is an antibacterial agent characterized by low hemolytic toxicity and a dual-target mechanism of action (MOA). It promotes FtsZ protein polymerization, increases bacterial membrane permeability, and inhibits biofilm formation. The resistance rate of MA220607 is low, with MICs against Gram-positive bacteria and Gram-negative bacteria ranging from 0.062-2 μg/mL and 0.5-4 μg/mL, respectively [1].
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  • 供应商
    TargetMolSC
    规格
    货期
    10-14周
    纯度
    -
    待询
    1

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