Name: NTPAN-MI
Rating: 5 (10 reviews)

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sdf 文件

结构编辑

类似物检索

HIT ID:HIT218848606
Cas No:2411398-95-1
常用名:NTPAN-MI
IUPAC:3,3-bis[4-(dimethylamino)phenyl]-2-[4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl]prop-2-enenitrile
IUPAC:3,3-bis[4-(dimethylamino)phenyl]-2-[4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl]prop-2-enenitrile
InChI key:CGOIFUPZTOUIMX-UHFFFAOYSA-N

分子式:C29H26N4O2
分子量:462.553
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CN(C)c1ccc(cc1)C(=C(C#N)c1ccc(cc1)N1C(=O)C=CC1=O)c1ccc(cc1)N(C)C
SMILES:CN(C)c1ccc(cc1)C(=C(C#N)c1ccc(cc1)N1C(=O)C=CC1=O)c1ccc(cc1)N(C)C

NTPAN-MI is a fluorescent probe selectively activated upon labeling unfolded proteins with exposed thiols, thereby reporting on the extent of proteostasis [1].

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