Name: Pomalidomide-5-C5-NH2 hydrochloride
Rating: 5 (10 reviews)

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HIT ID:HIT218848760
Cas No:2925306-39-2
常用名:Pomalidomide-5-C5-NH2 hydrochloride
常用名:Pomalidomide-5-C5-NH2 hydrochloride
IUPAC:5-[(5-aminopentyl)amino]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride
IUPAC:5-[(5-aminopentyl)amino]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride
InChI key:IFCYILIKWPEZTC-UHFFFAOYSA-N

分子式:C18H23ClN4O4
分子量:394.86
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:Cl.NCCCCCNc1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1
SMILES:Cl.NCCCCCNc1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1

Pomalidomide-5-C5-NH2 hydrochloride is a Pomalidomide-based cereblon (CRBN) ligand used for the recruitment of CRBN protein and can be linked to a protein ligand via a linker to form PROTAC [1].

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