Tubulin inhibitor 41 | CAS 2770273-12-4 | AnyMole

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HIT218849071

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HIT218849071

HIT ID:HIT218849071
Cas No:2770273-12-4
常用名:Tubulin inhibitor 41
IUPAC:2-amino-9-methyl-4-phenyl-4H-chromeno[8,7-b]pyridine-3-carbonitrile
IUPAC:2-amino-9-methyl-4-phenyl-4H-chromeno[8,7-b]pyridine-3-carbonitrile
InChI key:UCKRTNLJGZCCDX-UHFFFAOYSA-N

分子式:C20H15N3O
分子量:313.36
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:Cc1ccc2ccc3C(C(C#N)=C(N)Oc3c2n1)c1ccccc1
SMILES:Cc1ccc2ccc3C(C(C#N)=C(N)Oc3c2n1)c1ccccc1

Tubulin inhibitor 41 (Compd D19) is a promising lead compound for glioblastoma treatment, known for its ability to penetrate the blood-brain barrier (BBB). It functions as a tubulin inhibitor, inducing G2/M phase arrest, leading to cell apoptosis, and inhibiting the migration of U87 cells [1].

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10-14周
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