PBD-monoamide | CAS 2093165-00-3 | AnyMole

有库存

HIT218849331

sdf 文件

结构编辑

类似物检索

HIT218849331

HIT ID:HIT218849331
Cas No:2093165-00-3
常用名:PBD-monoamide
IUPAC:(7S)-13-methoxy-12-[(5-{[(7S)-13-methoxy-5-methylidene-2-oxo-3,9-diazatricyclo[8.4.0.0^{3,7}]tetradeca-1(14),8,10,12-tetraen-12-yl]oxy}pentyl)oxy]-5-methylidene-3,9-diazatricyclo[8.4.0.0^{3,7}]tetradeca-1(10),11,13-triene-2,8-dione
IUPAC:(7S)-13-methoxy-12-[(5-{[(7S)-13-methoxy-5-methylidene-2-oxo-3,9-diazatricyclo[8.4.0.0^{3,7}]tetradeca-1(14),8,10,12-tetraen-12-yl]oxy}pentyl)oxy]-5-methylidene-3,9-diazatricyclo[8.4.0.0^{3,7}]tetradeca-1(10),11,13-triene-2,8-dione
InChI key:VURHXTHIYXCIAA-LVXARBLLSA-N

分子式:C33H36N4O7
分子量:600.672
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:[H][C@@]12CC(=C)CN1C(=O)c1cc(OC)c(OCCCCCOc3cc4NC(=O)[C@]5([H])CC(=C)CN5C(=O)c4cc3OC)cc1N=C2
SMILES:[H][C@@]12CC(=C)CN1C(=O)c1cc(OC)c(OCCCCCOc3cc4NC(=O)[C@]5([H])CC(=C)CN5C(=O)c4cc3OC)cc1N=C2

PBD-monoamide, a modified pyrrolobenzodiazepine (PBD) dimer, functions as an ADC cytotoxin. It is utilized in synthesizing DHES0815A (an HER2 ADC) and possesses DNA-binding activity that reduces cell viability [1].

市场产品/服务共显示1个结果

供应商
TargetMolSC
规格
货期
10-14周
纯度
-
待询
1

寻找合适的化合物库

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

TargetMol | Target Loading

正在加载 ~