Name: Adipokinetic hormone II (Locusta migratoria)
Rating: 5 (10 reviews)

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HIT ID:HIT218850950
Cas No:98968-94-6
常用名:Adipokinetic hormone II (Locusta migratoria)
常用名:Adipokinetic hormone II (Locusta migratoria)
IUPAC:(2S)-N-[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}methyl)carbamoyl]ethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-phenylethyl]-2-[(2S)-4-methyl-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}pentanamido]butanediamide
IUPAC:(2S)-N-[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S)-1-carbamoyl-2-(1H-indol-3-yl)ethyl]carbamoyl}methyl)carbamoyl]ethyl]carbamoyl}-2-hydroxyethyl]carbamoyl}-2-phenylethyl]-2-[(2S)-4-methyl-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}pentanamido]butanediamide
InChI key:KMVRKMSUXFKTDO-RKNQSKIKSA-N

分子式:C43H57N11O11
分子量:903.995
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CC(C)C[C@H](NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
SMILES:CC(C)C[C@H](NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O

Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II)，一昆虫AKH，可提升脂肪体cAMP水平。AKHs通过其受体和Gs蛋白相互作用，增强cAMP生成与糖原磷酸化酶活性，从而直接调控飞蝗脂肪体中碳水化合物与脂质的动员。

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