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  3. HIT218852184
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HIT218852184
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HIT218852184
  • HIT ID:HIT218852184
  • Cas No:236095-24-2
  • 常用名:Camsirubicin HCl
  • IUPAC:(8R,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyethyl)-12-imino-1-methoxy-5,7,8,9,10,12-hexahydrotetracen-5-one hydrochloride
    IUPAC:(8R,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyethyl)-12-imino-1-methoxy-5,7,8,9,10,12-hexahydrotetracen-5-one hydrochloride
  • InChI key:QVPRMGHPBJJSRU-IGAJXZAQSA-N
  • 分子式:C27H33ClN2O9
  • 分子量:565.02
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:Cl.COc1cccc2C(=O)c3c(O)c4C[C@@](O)(CCO)C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=N)c12
    SMILES:Cl.COc1cccc2C(=O)c3c(O)c4C[C@@](O)(CCO)C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=N)c12
  • Camsirubicin, also known as GPX-150, MNPR-201, and CNDO1011, is a synthetic non-cardiotoxic analogue of the anthracycline antibiotic doxorubicin with potential antineoplastic activity. Anthracycline analogue GPX-150 intercalates DNA and impedes the activity of topoisomerase II, inducing single and double-stranded breaks in DNA; inhibiting DNA replication and/or repair, transcription, and protein synthesis; and activating tumor cell apoptosis.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    6-8周
    纯度
    -
    ¥ 10,600.00
    1

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