Name: Tuftsin diacetate
Rating: 5 (10 reviews)

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sdf 文件

结构编辑

类似物检索

HIT ID:HIT218852378
Cas No:72103-53-8
常用名:Tuftsin diacetate
IUPAC:(2S)-2-{[(2S)-1-[(2S)-6-amino-2-[(2S,3R)-2-amino-3-hydroxybutanamido]hexanoyl]pyrrolidin-2-yl]formamido}-5-carbamimidamidopentanoic acid; bis(acetic acid)
IUPAC:(2S)-2-{[(2S)-1-[(2S)-6-amino-2-[(2S,3R)-2-amino-3-hydroxybutanamido]hexanoyl]pyrrolidin-2-yl]formamido}-5-carbamimidamidopentanoic acid; bis(acetic acid)
InChI key:YIIURIAYCWLLNZ-DZOCJTNESA-N

分子式:C25H48N8O10
分子量:620.705
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CC(O)=O.CC(O)=O.C[C@@H](O)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O
SMILES:CC(O)=O.CC(O)=O.C[C@@H](O)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

Tuftsin diacetate, a tetrapeptide (Thr-Lys-Pro-Arg), is a macrophage/microglial activator found in the Fc-domain of the heavy chain of immunoglobulin G. It possesses a broad spectrum of activities related to immune system function, exerting effects primarily on phagocytic cells, notably on macrophages.

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