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  3. HIT218963976
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HIT218963976
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HIT218963976
  • HIT ID:HIT218963976
  • Cas No:118908-07-9
  • 常用名:EICAR
  • IUPAC:1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-ethynyl-1H-imidazole-4-carboxamide
    IUPAC:1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-ethynyl-1H-imidazole-4-carboxamide
  • InChI key:SWQQELWGJDXCFT-PNHWDRBUSA-N
  • 分子式:C11H13N3O5
  • 分子量:267.241
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:NC(=O)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1C#C
    SMILES:NC(=O)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c1C#C
  • EICAR is a drug which acts as an inhibitor of the enzyme IMP dehydrogenase. It is a nucleoside derivative which has both anti-cancer and antiviral effects, and was originally developed for the treatment of leukemia, but was unsuccessful in human clinical trials. It has broad spectrum antiviral effects with activity against vaccinia virus, Semliki forest virus, Junin virus, reovirus, influenza, measles virus and respiratory syncytial virus among others, although it is not active against SARS. This useful spectrum of activity means that EICAR and related derivatives continue to be investigated for the treatment of viral diseases.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    10-14周
    纯度
    -
    ¥ 21,600.00
    1

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