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HIT218964391
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HIT218964391
  • HIT ID:HIT218964391
  • Cas No:219657-36-0
  • 常用名:Eprociclovir Na
  • IUPAC:sodium [(1R,2S)-2-[(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)methyl]-2-(hydroxymethyl)cyclopropyl]methanolate
    IUPAC:sodium [(1R,2S)-2-[(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)methyl]-2-(hydroxymethyl)cyclopropyl]methanolate
  • InChI key:JMHMVEFTMFVFGE-BJUCTQDSSA-N
  • 分子式:C11H14N5NaO3
  • 分子量:287.255
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:[Na+].Nc1nc(=O)c2ncn(C[C@]3(CO)C[C@H]3C[O-])c2[nH]1
    SMILES:[Na+].Nc1nc(=O)c2ncn(C[C@]3(CO)C[C@H]3C[O-])c2[nH]1
  • Eprociclovir Na is the salt form of Eprociclovir, also known as A-5021, a new acyclovir analogue and a potent inhibitor of EHV1 replication and may have potential for the treatment and/or prophylaxis of infections with this virus. Eprociclovir possess potent anti-herpetic activity against most human herpesviruses. A-5021 proved to be about 15-fold more potent than acyclovir in inhibiting viral replication. Eprociclovir inhibits murine herpetic keratitis. A-5021 eyedrops, which are easily applied onto the affected cornea, ameliorated clinical scores and suppressed virus growth. Eprociclovir is a promising alternative treatment of herpetic keratitis.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    10-14周
    纯度
    -
    ¥ 16,100.00
    1

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