Name: AUR1545
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT219251475
Cas No:3031593-79-7
常用名:AUR1545
别名:AUR 1545
IUPAC:3-(5-{4-[(1-{4-[(3R,5R)-5-[(5-bromo-1-methyl-6-oxo-1,6-dihydropyridazin-4-yl)amino]-1-methylpiperidin-3-yl]benzoyl}piperidin-4-yl)methyl]piperazin-1-yl}-1-oxo-2,3-dihydro-1H-isoindol-2-yl)piperidine-2,6-dione
IUPAC:3-(5-{4-[(1-{4-[(3R,5R)-5-[(5-bromo-1-methyl-6-oxo-1,6-dihydropyridazin-4-yl)amino]-1-methylpiperidin-3-yl]benzoyl}piperidin-4-yl)methyl]piperazin-1-yl}-1-oxo-2,3-dihydro-1H-isoindol-2-yl)piperidine-2,6-dione
InChI key:CNPXSLCFWMPKRQ-BFFVTFPMSA-N

分子式:C41H50BrN9O5
分子量:828.813
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CN1C[C@@H](C[C@@H](C1)c1ccc(cc1)C(=O)N1CCC(CN2CCN(CC2)c2ccc3C(=O)N(Cc3c2)C2CCC(=O)NC2=O)CC1)Nc1cnn(C)c(=O)c1Br
SMILES:CN1C[C@@H](C[C@@H](C1)c1ccc(cc1)C(=O)N1CCC(CN2CCN(CC2)c2ccc3C(=O)N(Cc3c2)C2CCC(=O)NC2=O)CC1)Nc1cnn(C)c(=O)c1Br

AUR1545 is a selective KAT2A/KAT2B degradator exhibiting inhibitory activity against cancer models including AML, SCLC, and NEPC, and suppressing tumour growth in the NCI-H1048 xenograft model.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~