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  3. HIT219461942
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HIT219461942
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HIT219461942
  • HIT ID:HIT219461942
  • Cas No:189638-30-0
  • 常用名:Fabomotizole dihydrochloride
  • IUPAC:6-ethoxy-2-{[2-(morpholin-4-yl)ethyl]sulfanyl}-1H-1,3-benzodiazole dihydrochloride
    IUPAC:6-ethoxy-2-{[2-(morpholin-4-yl)ethyl]sulfanyl}-1H-1,3-benzodiazole dihydrochloride
  • InChI key:OFMVMQZFMVQDFO-UHFFFAOYSA-N
  • 分子式:C15H23Cl2N3O2S
  • 分子量:380.33
  • 氢键供体数 (HBD):
  • 氢键受体数 (HBA):
  • LogP:
  • SMILES:Cl.Cl.CCOc1ccc2nc(SCCN3CCOCC3)[nH]c2c1
    SMILES:Cl.Cl.CCOc1ccc2nc(SCCN3CCOCC3)[nH]c2c1
  • Fabomotizole, also known as Afobazole, Obenoxazine and CM346, is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors.
市场产品/服务共显示1个结果
  • 供应商
    TargetMolSC
    规格
    货期
    1-2周
    纯度
    -
    ¥ 10,600.00
    1

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