Name: PHA 543613 hydrochloride
Rating: 5 (10 reviews)

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HIT ID:HIT219465297
Cas No:1586767-92-1
常用名:PHA 543613 hydrochloride
IUPAC:N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]furo[2,3-c]pyridine-5-carboxamide hydrochloride
IUPAC:N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]furo[2,3-c]pyridine-5-carboxamide hydrochloride
InChI key:YMTPSZUBRSEWNY-ZOWNYOTGSA-N

分子式:C15H18ClN3O2
分子量:307.78
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:Cl.O=C(N[C@H]1CN2CCC1CC2)c1cc2ccoc2cn1
SMILES:Cl.O=C(N[C@H]1CN2CCC1CC2)c1cc2ccoc2cn1

PHA-543613 hydrochloride acts as a potent and selective agonist for the α7 subtype of neural nicotinic acetylcholine receptors, with a high level of brain penetration and good oral bioavailability. It is under development as a possible treatment for cognitive deficits in schizophrenia.

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