Name: Alexa fluor 647 maleimide
Rating: 5 (10 reviews)

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HIT ID:HIT219476038
Cas No:
常用名:Alexa fluor 647 maleimide
别名:3H-Indolium, 2-[5-[1,3-dihydro-3,3-dimethyl-5-sulfo-1-(3-sulfopropyl)-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-3-[5-[[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]amino]-5-oxopentyl]-3-methyl-5-sulfo-1-(3-sulfopropyl)-, inner salt
别名:3H-Indolium, 2-[5-[1,3-dihydro-3,3-dimethyl-5-sulfo-1-(3-sulfopropyl)-2H-indol-2-ylidene]-1,3-pentadien-1-yl]-3-[5-[[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethyl]amino]-5-oxopentyl]-3-methyl-5-sulfo-1-(3-sulfopropyl)-, inner salt
IUPAC:2-{5-[3,3-dimethyl-5-sulfo-1-(3-sulfopropyl)-2,3-dihydro-1H-indol-2-ylidene]penta-1,3-dien-1-yl}-3-(4-{[2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl]carbamoyl}butyl)-3-methyl-5-sulfo-1-(3-sulfonatopropyl)-3H-indol-1-ium
IUPAC:2-{5-[3,3-dimethyl-5-sulfo-1-(3-sulfopropyl)-2,3-dihydro-1H-indol-2-ylidene]penta-1,3-dien-1-yl}-3-(4-{[2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl]carbamoyl}butyl)-3-methyl-5-sulfo-1-(3-sulfonatopropyl)-3H-indol-1-ium
InChI key:DWGFRMIASUGRKA-UHFFFAOYSA-N

分子式:C41H50N4O15S4
分子量:967.1
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CC1(C)C(=CC=CC=CC2=[N+](CCCS([O-])(=O)=O)c3ccc(cc3C2(C)CCCCC(=O)NCCN2C(=O)C=CC2=O)S(O)(=O)=O)N(CCCS(O)(=O)=O)c2ccc(cc12)S(O)(=O)=O
SMILES:CC1(C)C(=CC=CC=CC2=[N+](CCCS([O-])(=O)=O)c3ccc(cc3C2(C)CCCCC(=O)NCCN2C(=O)C=CC2=O)S(O)(=O)=O)N(CCCS(O)(=O)=O)c2ccc(cc12)S(O)(=O)=O

Alexa fluor 647 maleimide 是一种水溶性荧光染料，能在广泛的生理条件下保持稳定。Alexa fluor 647 maleimide 可通过与巯基选择性反应，实现荧光基团与蛋白质的共价连接，从而实现高灵敏度与高特异性标记，即使在极低浓度下也能检测蛋白质。Alexa fluor 647 maleimide 被广泛应用于蛋白质表达和定位研究，并可与抗体偶联，用于细胞表面抗原或组织中特定蛋白的标记 [Ex/Em(nm) = 651/671]。

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