Name: Bulevirtide
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT219478899
Cas No:2012558-47-1
常用名:Bulevirtide
别名:布来韦肽, Myrcludex B, MyrB
IUPAC:(4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-5-amino-1-{[(1S)-1-[(carbamoylmethyl)carbamoyl]-2-methylpropyl]carbamoyl}pentyl]carbamoyl}-2-carbamoylethyl]carbamoyl}ethyl]carbamoyl}-4-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-3-carbamoyl-2-{[(2S)-1-[(2S)-3-carbamoyl-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-3-carbamoyl-2-[(2S)-3-carbamoyl-2-[(2S)-2-[(2S)-3-carbamoyl-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-4-carbamoyl-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(2S)-2-{[(2S)-1-[(2S)-3-carbamoyl-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-3-carbamoyl-2-[(2S,3R)-3-hydroxy-2-(2-tetradecanamidoacetamido)butanamido]propanamido]-4-methylpentanamido]-3-hydroxypropanamido]-3-methylbutanoyl]pyrrolidin-2-yl]formamido}propanoyl]pyrrolidin-2-yl]formamido}-4-methylpentanamido]acetamido}-3-phenylpropanamido]-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}-3-carboxypropanamido]-3-(1H-imidazol-5-yl)propanamido]butanamido]-4-methylpentanamido]-3-carboxypropanoyl]pyrrolidin-2-yl]formamido}propanamido]-3-phenylpropanamido]acetamido}propanamido]propanamido]-3-hydroxypropanamido]propanamido]propanoyl]pyrrolidin-2-yl]formamido}-3-carboxypropanamido]-3-(1H-indol-3-yl)propanamido]-3-carboxypropanamido]-3-phenylpropanamido]propanoyl]pyrrolidin-2-yl]formamido}propanamido]hexanamido]-3-carboxypropanamido]-3-(1H-imidazol-5-yl)propanamido]-3-(1H-indol-3-yl)propanoyl]pyrrolidin-2-yl]formamido}butanoic acid
IUPAC:(4S)-4-{[(1S)-1-{[(1S)-1-{[(1S)-5-amino-1-{[(1S)-1-[(carbamoylmethyl)carbamoyl]-2-methylpropyl]carbamoyl}pentyl]carbamoyl}-2-carbamoylethyl]carbamoyl}ethyl]carbamoyl}-4-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-3-carbamoyl-2-{[(2S)-1-[(2S)-3-carbamoyl-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-3-carbamoyl-2-[(2S)-3-carbamoyl-2-[(2S)-2-[(2S)-3-carbamoyl-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-4-carbamoyl-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(2S)-2-{[(2S)-1-[(2S)-3-carbamoyl-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-3-carbamoyl-2-[(2S,3R)-3-hydroxy-2-(2-tetradecanamidoacetamido)butanamido]propanamido]-4-methylpentanamido]-3-hydroxypropanamido]-3-methylbutanoyl]pyrrolidin-2-yl]formamido}propanoyl]pyrrolidin-2-yl]formamido}-4-methylpentanamido]acetamido}-3-phenylpropanamido]-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}-3-carboxypropanamido]-3-(1H-imidazol-5-yl)propanamido]butanamido]-4-methylpentanamido]-3-carboxypropanoyl]pyrrolidin-2-yl]formamido}propanamido]-3-phenylpropanamido]acetamido}propanamido]propanamido]-3-hydroxypropanamido]propanamido]propanoyl]pyrrolidin-2-yl]formamido}-3-carboxypropanamido]-3-(1H-indol-3-yl)propanamido]-3-carboxypropanamido]-3-phenylpropanamido]propanoyl]pyrrolidin-2-yl]formamido}propanamido]hexanamido]-3-carboxypropanamido]-3-(1H-imidazol-5-yl)propanamido]-3-(1H-indol-3-yl)propanoyl]pyrrolidin-2-yl]formamido}butanoic acid
InChI key:WQNDXLHKAMIGEX-WOAPPVHJSA-N

分子式:C248H355N65O72
分子量:5398.951
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CCCCCCCCCCCCCC(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)NCC(N)=O
SMILES:CCCCCCCCCCCCCC(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)NCC(N)=O

Bulevirtide（Myrcludex B）是钠牛磺胆酸共转运多肽的合成脂肽抑制剂，能有效阻断乙肝病毒与丁肝病毒对肝细胞的侵入（包括代偿期肝硬化病例），在慢性丁型肝炎研究方面具有重要应用前景。

市场产品/服务共显示1个结果

供应商
TargetMolSC
规格
货期
5日内发货
纯度
-
¥ 799.00
1

寻找合适的化合物库

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~