Name: AZD2389
Rating: 5 (10 reviews)

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HIT ID:HIT219599806
Cas No:2791472-12-1
常用名:AZD2389
别名:AZD-2389, AZD 2389
IUPAC:N-{2-[(4R)-4-cyano-1,3-thiazolidin-3-yl]-2-oxoethyl}-6-(morpholin-4-yl)quinoline-4-carboxamide
IUPAC:N-{2-[(4R)-4-cyano-1,3-thiazolidin-3-yl]-2-oxoethyl}-6-(morpholin-4-yl)quinoline-4-carboxamide
InChI key:GECJKRWOVGXGCO-OAHLLOKOSA-N

分子式:C20H21N5O3S
分子量:411.48
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:O=C(CNC(=O)c1ccnc2ccc(cc12)N1CCOCC1)N1CSC[C@H]1C#N
SMILES:O=C(CNC(=O)c1ccnc2ccc(cc12)N1CCOCC1)N1CSC[C@H]1C#N

AZD2389 is an effective and orally active FAP inhibitor that improves histological fibrosis and increases intact α2-AP, suitable for studying metabolic dysfunction-associated steatohepatitis.

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