Name: Hibarimicin D
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT219599964
Cas No:208588-87-8
常用名:Hibarimicin D
IUPAC:5-{[(2S,5S,6R)-5-{[(2R,4R,5S,6S)-5-acetyl-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-15-(9-{[(2S,5S,6R)-5-{[(2R,5S,6S)-5-acetyl-5-hydroxy-6-methyloxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-7-{[(2S,4R,5R,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-1,8,10,10a,12-pentahydroxy-3,4-dimethoxy-11-oxo-10-propyl-6,6a,7,8,9,10,10a,11-octahydrotetracen-2-yl)-7-{[(2S,4R,5R,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-6,9,12,19-tetrahydroxy-16-methoxy-4-propyl-3-oxapentacyclo[9.8.0.0^{2,8}.0^{4,9}.0^{13,18}]nonadeca-1(11),12,15,18-tetraene-10,14,17-trione
IUPAC:5-{[(2S,5S,6R)-5-{[(2R,4R,5S,6S)-5-acetyl-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-15-(9-{[(2S,5S,6R)-5-{[(2R,5S,6S)-5-acetyl-5-hydroxy-6-methyloxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-7-{[(2S,4R,5R,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-1,8,10,10a,12-pentahydroxy-3,4-dimethoxy-11-oxo-10-propyl-6,6a,7,8,9,10,10a,11-octahydrotetracen-2-yl)-7-{[(2S,4R,5R,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-6,9,12,19-tetrahydroxy-16-methoxy-4-propyl-3-oxapentacyclo[9.8.0.0^{2,8}.0^{4,9}.0^{13,18}]nonadeca-1(11),12,15,18-tetraene-10,14,17-trione
InChI key:NBQIPBWBWLRUKS-ADTODSHXSA-N

分子式:C85H112O38
分子量:1741.793
氢键供体数 (HBD):
氢键受体数 (HBA):
LogP:
SMILES:CCCC12OC3C(C(O[C@H]4C[C@@H](O)[C@@H](O)[C@H](C)O4)C(O)C1O[C@H]1CC[C@H](O[C@H]4C[C@@H](O)[C@](O)([C@H](C)O4)C(C)=O)[C@@H](C)O1)C2(O)C(=O)c1c(O)c2C(=O)C(=C(OC)C(=O)c2c(O)c31)c1c(O)c2c(O)c3C(=O)C4(O)C(Cc3cc2c(OC)c1OC)C(O[C@H]1C[C@@H](O)[C@@H](O)[C@H](C)O1)C(O)C(O[C@H]1CC[C@H](O[C@H]2CC[C@](O)([C@H](C)O2)C(C)=O)[C@@H](C)O1)C4(O)CCC
SMILES:CCCC12OC3C(C(O[C@H]4C[C@@H](O)[C@@H](O)[C@H](C)O4)C(O)C1O[C@H]1CC[C@H](O[C@H]4C[C@@H](O)[C@](O)([C@H](C)O4)C(C)=O)[C@@H](C)O1)C2(O)C(=O)c1c(O)c2C(=O)C(=C(OC)C(=O)c2c(O)c31)c1c(O)c2c(O)c3C(=O)C4(O)C(Cc3cc2c(OC)c1OC)C(O[C@H]1C[C@@H](O)[C@@H](O)[C@H](C)O1)C(O)C(O[C@H]1CC[C@H](O[C@H]2CC[C@](O)([C@H](C)O2)C(C)=O)[C@@H](C)O1)C4(O)CCC

Hibarimicin D 是一种酪氨酸激酶抑制剂，选择性抑制 src 酪氨酸激酶活性，并且对革兰氏阳性菌表现出中等抗菌活性，最低抑制浓度 (MIC) 为 0.8-12.56 μg/mL。

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~